How do you recognise a suspicious mole? The ABCDE rule explained

Updated on 10 November 2026 · 8 min read

In short: A mole should be che­cked by a doc­tor if it chan­ges, looks cle­ar­ly dif­fe­rent from your other moles or cau­ses sym­ptoms such as itching or blee­ding. The ABCDE rule helps you pay atten­ti­on to shape, bor­der, colour, size and chan­ge over time. It is a gui­de and can neither con­firm nor rule out skin can­cer. A sin­gle noti­ceable chan­ge is reason enough to have a mole exami­ned, even if it is small and does not hurt.

What makes a mole look suspicious?

A mole, known medi­cal­ly as a nae­vus, is usual­ly benign. The aim is the­r­e­fo­re not to label as many spots as pos­si­ble as sus­pi­cious. It is more useful to get to know your own skin: which moles have been the­re for a long time, what do they look like, and does one of them stand out from the usu­al pattern?

In der­ma­to­lo­gy, a mole that stands out like this is some­ti­mes cal­led the «ugly duck­ling». If, for exam­p­le, you have many simi­lar light brown moles and noti­ce one spot among them with a cle­ar­ly dif­fe­rent colour, you should show it to a doc­tor. The same appli­es to a mole who­se shape is noti­ce­ab­ly dif­fe­rent from the others. A dif­fe­rence is not a can­cer dia­gno­sis, but it deser­ves attention.

Look at are­as of skin wit­hout any exis­ting mole as well. A mela­n­o­ma can deve­lop on skin that pre­vious­ly loo­ked nor­mal. If you only check the moles you alre­a­dy know, you may miss a new change.

The ABCDE rule as a checklist

Take your time going through the fol­lo­wing fea­tures. You do not need to count points, and a mole does not have to «meet» every let­ter. Descri­be as spe­ci­fi­cal­ly as you can what you have noti­ced. The medi­cal assess­ment takes into account the over­all appearance of a skin lesi­on and how it has developed.

Fea­ture What to look at What can be a war­ning sign
A: Asym­me­try Compa­re the two hal­ves of the spot. The hal­ves cle­ar­ly dif­fer in shape.
B: Bor­der Look at whe­re the spot meets the sur­roun­ding skin. The edge looks rag­ged, irre­gu­lar or blurred.
C: Colour Noti­ce how the shades are distributed. Light and dark are­as alter­na­te uneven­ly, for exam­p­le brown and black, or with addi­tio­nal red­dish areas.
D: Dia­me­ter Note the size and compa­re it with how it used to be. A mole is get­ting big­ger. Size alo­ne does not allow a relia­ble jud­ge­ment, howe­ver: small mela­no­mas occur too.
E: Evo­lu­ti­on Ask yours­elf what has changed. The shape, colour, size or sur­face looks dif­fe­rent from before.

You may have come across a dif­fe­rent set of let­ters. The Swiss Can­cer League uses the ABCD rule, in which D stands for dyna­mics. This refers to chan­ges in size, colour, shape or thic­k­ness. In the ABCDE ver­si­on explai­ned here, E for evo­lu­ti­on covers the same idea. The mes­sa­ge is the same: chan­ges should be asses­sed by a doctor.

Changes the rule can miss

An even bor­der or a uni­form colour does not rule out mela­n­o­ma. Some mela­no­mas grow as a nodu­le and do not fit the usu­al ABCDE descrip­ti­on well. So also watch for a new rai­sed lesi­on that feels firm and grows quick­ly. Have it exami­ned prompt­ly, even if it looks round or symmetrical.

In Ger­man, mela­n­o­ma is com­mon­ly cal­led «black skin can­cer», which can be mis­lea­ding: a mela­n­o­ma does not have to be dark. It can, for exam­p­le, appear red­dish or skin-colou­red. A new, gro­wing skin lesi­on should the­r­e­fo­re not be con­side­red harm­less sim­ply becau­se it is pale.

Rai­sed does not auto­ma­ti­cal­ly mean dangerous

E is some­ti­mes explai­ned as ele­va­ti­on. Benign moles can also be rai­sed abo­ve the level of the skin. What mat­ters more than ele­va­ti­on alo­ne is whe­ther a lesi­on is new, chan­ging or gro­wing. Con­ver­se­ly, a flat mole is not auto­ma­ti­cal­ly harmless.

The check­list helps you noti­ce any­thing unu­su­al. A self-check that seems reassu­ring should never be a reason to igno­re a chan­ge or a fee­ling that some­thing is not right.

How to check your skin systematically

Use a full-length mir­ror and, whe­re nee­ded, a hand mir­ror. Someone you trust can look at are­as that are hard for you to see. Always fol­low the same order so that you do not only look at the easi­ly visi­ble moles on your arms and stomach.

  1. Front and sides: Look at your body from the front and from each side. Rai­se your arms so that your arm­pits are visi­ble too.
  2. Arms and hands: Check your upper arms, fore­arms, palms and fingernails.
  3. Legs and feet: Remem­ber the backs of your legs, the soles of your feet, the spaces bet­ween your toes and your toenails.
  4. Head and back: Use the hand mir­ror to look at the back of your neck, your scalp, your back and your buttocks. Part your hair to see the scalp more clearly.

Skin chan­ges can also occur in places that get litt­le sun. A new dark area under a nail wit­hout any obvious inju­ry should be asses­sed by a doc­tor as well. So do not limit your atten­ti­on to the parts of the body that tan in summer.

If you noti­ce an unu­su­al spot, wri­te down whe­re it is and what has chan­ged. If you alre­a­dy have older pho­tos, you can bring them to your appoint­ment. But if a lesi­on looks sus­pi­cious, do not start a long peri­od of obser­va­ti­on just to coll­ect a series of pic­tures first.

When should you see a doctor?

Arran­ge a prompt assess­ment if you dis­co­ver a new, unu­su­al mole or if an exis­ting one chan­ges. This appli­es in par­ti­cu­lar to rapid growth, repea­ted blee­ding wit­hout an obvious inju­ry, oozing or a spot that does not heal. Itching, pain or new crus­ting are also reasons to have a skin lesi­on examined.

Do not wait until your next sche­du­led skin check. When you book the appoint­ment, say which chan­ge you have noti­ced and how long it has been the­re. This allows the prac­ti­ce to judge how urgent it is. You are wel­co­me to cont­act us for a mole check in Zurich. Your fami­ly doc­tor can also be a first point of contact.

Whe­ther regu­lar checks make sen­se in addi­ti­on depends on your per­so­nal risk. Rele­vant fac­tors include many or unu­su­al moles, a pre­vious skin can­cer, mela­n­o­ma in clo­se rela­ti­ves or a wea­k­en­ed immu­ne sys­tem. Dis­cuss a sui­ta­ble fol­low-up plan with your doc­tor. What deter­mi­nes the inter­vals is explai­ned in our artic­le How often should moles be che­cked? A new­ly noti­ced chan­ge is asses­sed inde­pendent­ly of this plan.

How we assess a suspicious mole

At the Swiss Der­ma Cli­nic in Zurich, we exami­ne moles with a der­ma­to­scope. We also offer com­pu­ter-assis­ted digi­tal video der­ma­to­sco­py. Skin lesi­ons are pho­to­gra­phed and the images are stored for later com­pa­ri­son. At fol­low-up visits, the image com­pa­ri­son is com­bi­ned with the phy­si­cal examination.

Show us the spot that worries you and descri­be what you have obser­ved. It helps, for exam­p­le, to men­ti­on that a pre­vious­ly flat spot can now be felt, or that it has bled wit­hout an obvious inju­ry. You do not need to be able to deci­de before­hand whe­ther it is skin cancer.

If a skin lesi­on remains sus­pi­cious, it may need to be remo­ved and the tis­sue exami­ned in a labo­ra­to­ry. Only this tis­sue exami­na­ti­on cla­ri­fies, whe­re the­re is such a sus­pi­ci­on, whe­ther a mela­n­o­ma is pre­sent. Our ser­vices also include out­pa­ti­ent sur­gery to remo­ve sus­pi­cious skin lesi­ons. Which assess­ment is appro­pria­te in your case depends on the medi­cal findings.

You can find more infor­ma­ti­on about the exami­na­ti­on and digi­tal docu­men­ta­ti­on on our page on skin can­cer scree­ning and mole checks.

Frequently asked questions

Do all ABCDE features have to apply?

No. A sin­gle war­ning sign or one clear chan­ge can be enough to jus­ti­fy an exami­na­ti­on. The rule is not a scoring sys­tem. Do not wait for itching or blee­ding to appear in addi­ti­on to a chan­ge in shape.

Can a very small mole be dangerous?

Yes. A small dia­me­ter does not rule out mela­n­o­ma. What also mat­ters is whe­ther the spot is chan­ging or looks dif­fe­rent from your other moles. Mea­su­ring the size yours­elf the­r­e­fo­re does not replace a medi­cal assessment.

Is a mole that does not hurt harmless?

No. A mela­n­o­ma can be pre­sent wit­hout pain or any other noti­ceable sym­ptoms. So pay atten­ti­on to visi­ble chan­ges as well. If a mole looks dif­fe­rent from befo­re, that alo­ne is a reason to seek medi­cal advice.

Does an itchy mole mean skin cancer?

Not auto­ma­ti­cal­ly. Itching alo­ne does not allow a dia­gno­sis. An itchy mole should still be asses­sed, espe­ci­al­ly if its appearance is chan­ging at the same time or if it bleeds or crusts over. At your appoint­ment, descri­be both the sym­ptoms and the visi­ble changes.

Does every suspicious mole have to be removed?

No. Sus­pi­cious first of all means that the skin lesi­on should be exami­ned more clo­se­ly. Benign lesi­ons can also show indi­vi­du­al war­ning signs. After the exami­na­ti­on, the doc­tor deci­des whe­ther moni­to­ring is suf­fi­ci­ent or whe­ther tis­sue needs to be exami­ned for a defi­ni­te answer.

This artic­le does not replace a medi­cal examination.

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