Botulinum toxin for migraine: relief for chronic headaches

Anyo­ne who regu­lar­ly suf­fers from migrai­nes knows how much they can rest­rict ever­y­day life. Both pro­fes­sio­nal­ly and pri­va­te­ly. Tho­se affec­ted descri­be the usual­ly very seve­re hea­da­ches as throb­bing, often on one side, accom­pa­nied by sen­si­ti­vi­ty to light, nau­sea or diz­ziness. The exact „pain pat­tern“ varies from per­son to per­son. If the hea­da­che occurs seve­ral days a month, we speak of a chro­nic migrai­ne. Clas­sic pain­kil­lers often reach their limits here. Botu­li­num is a pro­mi­sing the­ra­py concept.

 

When migraines become chronic

We speak of chro­nic migrai­ne when hea­da­ches occur on at least 15 days a month, at least 8 of which are accom­pa­nied by the typi­cal migrai­ne sym­ptoms. Migrai­ne is a dise­a­se that affects the sen­sa­ti­on of pain its­elf and the pro­ces­sing of ner­ve stimuli.

 

Tho­se affec­ted often report that the medi­ca­ti­on is not effec­ti­ve enough, is poor­ly tole­ra­ted or does not bring any sta­ble impro­ve­ment in the long term.

 

How botulinum works for migraines

Per­haps you know botu­li­num toxin from aes­the­tic medi­ci­ne? At the Swiss Der­ma Cli­nic in Zurich, for exam­p­le, we tre­at wrink­les or dro­o­ping eye­brows with the mus­cle-rela­xing sub­s­tance(read more). The acti­ve ingre­di­ent has also been used suc­cessful­ly in neu­ro­lo­gy for many years.

 

The mecha­nism of action? It is com­ple­te­ly dif­fe­rent from that of clas­sic pain­kil­lers. Botu­li­num toxin blocks the release of cer­tain mes­sen­ger sub­s­tances at the ner­ve endings that are invol­ved in pain trans­mis­si­on. The over­ac­ti­vi­ty of the pain-media­ting ner­ve pathways is weakened.

 

Important: Pain is not pushed away, the trans­mis­si­on of sti­mu­li within the ner­vous sys­tem is calmed.

 

A look at the treatment

The the­ra­py is car­ri­ed out in defi­ned are­as of the head, neck and should­ers. Botu­li­num toxin is injec­ted in very small quan­ti­ties into spe­ci­fic mus­cle and ner­ve regi­ons. Simi­lar to an injec­tion with fine need­les and within a few minu­tes. Anes­the­sia is gene­ral­ly not neces­sa­ry – the­re is also no downtime.

 

The effect of botu­li­num toxin does not start imme­dia­te­ly; it deve­lo­ps con­ti­nuous­ly over one to two weeks.

 

Who is the treatment suitable for?

Botu­li­num toxin is only appro­ved for the tre­at­ment of chro­nic migrai­ne. It is not appro­ved for the tre­at­ment of occa­sio­nal or epi­so­dic migrai­nes. The most important pre­re­qui­si­te is the­r­e­fo­re an appro­pria­te dia­gno­sis by a neurologist.

 

 

Important regu­la­ti­ons: Botu­li­num toxin for chro­nic headaches

 

The use of botu­li­num toxin for chro­nic migrai­nes is sub­ject to strict regu­la­ti­ons and always requi­res a spe­cia­list dia­gno­sis and assess­ment by a neu­ro­lo­gist. Peo­p­le with many migrai­ne days per month, for whom pro­phyl­ac­tic the­ra­pies do not work suf­fi­ci­ent­ly and who have pro­blems with medi­ca­ti­on-rela­ted side effects, are par­ti­cu­lar­ly likely to benefit.

The risk of side effects is very low when used by a spe­cia­list. Small, tem­po­ra­ry blee­ding in the area of the punc­tu­re sites is pos­si­ble. In some cases, local ten­der­ness or a fee­ling of ten­si­on may occur in the trea­ted area.

 

Botulinum toxin: part of a holistic concept?

Migrai­nes are com­plex. Tre­at­ment with botu­li­num toxin does not auto­ma­ti­cal­ly replace other opti­ons; ins­tead, it is part of an indi­vi­dua­li­zed over­all con­cept. This includes, for example

  • adap­ting your lifestyle
  • Less stress, fewer migrai­ne triggers
  • Accom­pany­ing medication
  • Sport or rela­xa­ti­on techniques

 

Botu­li­num toxin can be an effec­ti­ve tre­at­ment opti­on if you have been pro­ven to suf­fer from chro­nic migrai­nes. The tre­at­ment is not an imme­dia­te solu­ti­on, but an approach that is desi­gned for long-term pre­ven­ti­on. Whe­ther this is also sui­ta­ble for you can only be asses­sed during a spe­cia­list consultation.

 

 

Botulinum toxin – briefly explained

Botu­li­num toxin is a medi­cal agent that has been tried and tes­ted for many years. It can tem­po­r­a­ri­ly dam­pen cer­tain ner­ve impul­ses and thus relax over­ac­ti­ve mus­cles. Pain-con­duc­ting sti­mu­li are reduced.

In migrai­ne the­ra­py , the mus­cle rela­x­ant calms hyper­sen­si­ti­ve ner­ves that are invol­ved in the deve­lo­p­ment of chro­nic headaches.

The effect of botu­li­num toxin is tem­po­ra­ry and com­ple­te­ly rever­si­ble. The acti­ve ingre­di­ent is bro­ken down by the body after a few months. The tre­at­ment should be car­ri­ed out by an expe­ri­en­ced doc­tor and requi­res exten­si­ve spe­cia­list diagnostics.

 

 

FAQ

When does migrai­ne tre­at­ment with botu­li­num toxin make sense?

This approach is aimed at pati­ents with chro­nic migrai­nes (at least 15 hea­da­che days per month over a peri­od of at least 3 months). The pre­re­qui­si­tes are a spe­cia­list (neu­ro­lo­gi­cal) dia­gno­sis and pre­vious tre­at­ment with con­ven­tio­nal medication.

 

How quick­ly does botu­li­num toxin take effect in migraines?

The acti­ve ingre­di­ent is a mus­cle rela­x­ant that does not have an imme­dia­te pain-reli­e­ving effect, such as a pain­kil­ler. It has a pre­ven­ta­ti­ve effect and influen­ces the acti­vi­ty of pain-con­duc­ting ner­ves. The effect builds up gra­du­al­ly over a peri­od of around two weeks after the injec­tion and lasts for around three months. A sin­gle acu­te attack can­not be trea­ted with botu­li­num toxin. For a sta­ble impro­ve­ment, regu­lar tre­at­ments at fixed inter­vals are advisable.

 

Does the tre­at­ment have to be permanent?

Long-term tre­at­ment is not abso­lut­e­ly neces­sa­ry. Many pati­ents bene­fit from the the­ra­py for a cer­tain peri­od of time and then no lon­ger need it as their con­di­ti­on has sta­bi­li­zed. Others only need tre­at­ment in pha­ses. What makes sen­se depends on the indi­vi­du­al cour­se of the migraine.

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Fachärztin FMH,
Geschäftsführerin,
Ärztliche Leitung - Lia Georgouli
Evangelia (Lia) Georgouli is a board-certified specialist (FMH) in Dermatology and Venereology, as well as the Managing Director and Medical Director of Swiss Derma Clinic in Zurich. With her passion for skin health and aesthetic medicine, she offers state-of-the-art treatment methods individually tailored to her patients' needs. With her extensive experience in Switzerland, Germany, and Greece, along with continuous professional development, Georgouli stands for the highest quality and professionalism.
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